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Lamivudine-resistant variants of HIV-1 have been selected in cell culture.

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Dose reduction or discontinuation of interferon alfa, ribavirin, or both should also be considered if worsening clinical toxicities are observed, including hepatic decompensation (e.

So far only one adult (the so-called "") has been potentially cured and has been off of treatment since 2006 with no detectable virus.

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